Minoxidil is indicated in the treatment of androgenic alopecia in males and females and stabilization of hair loss in patients with androgenic alopecia, and also of alopecia areata.
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Splendora 5 belongs to a group of medicines called vasodilators. It is used to promote hair growth after hereditary hair loss (male pattern baldness). It is not used for sudden, patchy, or unexplained hair loss. Splendora 5% should only be applied directly to the scalp in the amount and manner indicated on the label or by your doctor.
No interaction found/established
Splendora 5% may be unsafe to use during pregnancy. Although there are limited studies on humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.
Splendora 5% is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
No interaction found/established
No interaction found/established
No interaction found/established
Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use.
Splendora 5% is a potassium channel opener. Its vasodilation action expands the blood vessels. Therefore, when it is applied to the scalp, it helps to increase blood flow. This increased blood flow provides more nutrition and oxygen to the hair follicles, which prevents hair cell death and also enhances new hair growth. This is how it works to treat your alopecia (hair loss).
If you miss a dose of Splendora 5%, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Minoxidil acts on hair follicles by dilating blood vessels and inhibiting androgens, which increases the supply of oxygen, blood, and nutrients to the hair follicles, thereby stimulating hair growth. After application, an average of 1.4% of the total dose was absorbed by the normal intact scalp. The topical absorption of minoxidil increases with increasing dose, thereby increasing the frequency of administration and decreasing the barrier function of the stratum corneum. Serum concentrations of minoxidil and the systemic effects of topical minoxidil are controlled by the rate of drug absorption through the skin. After topical discontinuation, approximately 95% of the systemic absorption is eliminated within 4 days. Minoxidil and its metabolites are mainly excreted in the urine.
Due to the increased absorption of minoxidil, minoxidil topical solution should not be used with other topical medications known to disrupt the stratum corneum barrier (such as tretinoin or anthralin). Although there is no clinical evidence, it is theoretically possible that the absorption of minoxidil may potentiate orthostatic hypotension caused by peripheral vasodilators.
Minoxidil topical solution is contraindicated in patients with a history of hypersensitivity to Minoxidil or any of the other ingredients in the formulation such as propylene glycol or ethanol.
Minoxidil topical solution should not be used during pregnancy and breastfeeding.
Store in a cool, dry place, protected from light. Keep out of the reach of children.
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